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T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster

T cell receptor (TCR) signaling is initiated and sustained in microclusters; however, it’s not known whether signaling also occurs in the TCR-rich central supramolecular activation cluster (cSMAC). We showed that the cSMAC formed by fusion of microclusters contained more CD45 than microclusters and...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Varma, Rajat, Campi, Gabriele, Yokosuka, Tadashi, Saito, Takashi, Dustin, Michael L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626533/
https://ncbi.nlm.nih.gov/pubmed/16860761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2006.04.010
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