The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts

Integrin-mediated cell adhesion to extracellular matrix proteins is known to promote cell survival, whereas detachment from the matrix can cause rapid apoptotic death in some cell types. Contrary to this paradigm, we show that fibroblast adhesion to the angiogenic matrix protein CCN1 (CYR61) induces...

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Main Authors: Todorovicç, Viktor, Chen, Chih-Chiun, Hay, Nissim, Lau, Lester F.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2005
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626352/
https://ncbi.nlm.nih.gov/pubmed/16275757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504015
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