The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts

Integrin-mediated cell adhesion to extracellular matrix proteins is known to promote cell survival, whereas detachment from the matrix can cause rapid apoptotic death in some cell types. Contrary to this paradigm, we show that fibroblast adhesion to the angiogenic matrix protein CCN1 (CYR61) induces...

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Hlavní autoři: Todorovicç, Viktor, Chen, Chih-Chiun, Hay, Nissim, Lau, Lester F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626352/
https://ncbi.nlm.nih.gov/pubmed/16275757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504015
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