Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia

1. Bradyzide is from a novel class of rodent-selective non-peptide B(2) bradykinin antagonists (1-(2-Nitrophenyl)thiosemicarbazides). 2. Bradyzide has high affinity for the rodent B(2) receptor, displacing [(3)H]-bradykinin binding in NG108-15 cells and in Cos-7 cells expressing the rat receptor wit...

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書誌詳細
主要な著者: Burgess, Gillian M, Perkins, Martin N, Rang, Humphrey P, Campbell, Elizabeth A, Brown, Michael C, McIntyre, Peter, Urban, Laszlo, Dziadulewicz, Edward K, Ritchie, Timothy J, Hallett, Allan, Snell, Christopher R, Wrigglesworth, Roger, Lee, Wai, Davis, Clare, Phagoo, Steve B, Davis, Andrew J, Phillips, Elsa, Drake, Gillian S, Hughes, Glyn A, Dunstan, Andrew, Bloomfield, Graham C
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621130/
https://ncbi.nlm.nih.gov/pubmed/10694205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703012
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