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Antihyperalgesic activity of a novel nonpeptide bradykinin B(1) receptor antagonist in transgenic mice expressing the human B(1) receptor
1. We describe the properties of a novel nonpeptide kinin B(1) receptor antagonist, NVP-SAA164, and demonstrate its in vivo activity in models of inflammatory pain in transgenic mice expressing the human B(1) receptor. 2. NVP-SAA164 showed high affinity for the human B(1) receptor expressed in HEK29...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576084/ https://ncbi.nlm.nih.gov/pubmed/15685199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706139 |
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