The identification of an orally active, nonpeptide bradykinin B(2) receptor antagonist, FR173657

1. An orally active, nonpeptide bradykinin (BK) B(2) receptor antagonist, FR173657 (E)-3-(6-acetamido-3 - pyridyl) - N - [N - [2 - 4 -dichloro-3-[(2-methyl-8-quinolinyl) oxymethyl]phenyl]-N-methylaminocarbonylmethyl]acrylamide) has been identified. 2. This compound displaced [(3)H]-BK binding to B(2...

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Detaylı Bibliyografya
Asıl Yazarlar: Asano, Masayuki, Inamura, Noriaki, Hatori, Chie, Sawai, Hiroe, Fujiwara, Tatsujiro, Katayama, Akira, Kayakiri, Hiroshi, Satoh, Shigeki, Abe, Yoshito, Inoue, Takayuki, Sawada, Yuki, Nakahara, Kunio, Oku, Teruo, Okuhara, Masakuni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564513/
https://ncbi.nlm.nih.gov/pubmed/9051299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700955
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