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Proinflammatory characteristics of a nonpeptide bradykinin mimic, FR190997, in vivo

1. Proinflammatory potency of the nonpeptide bradykinin (BK) B(2) receptor agonist FR190997 (8-[2,6-dichloro-3-[N-[(E)-4-(N-methylcarbamoyl)cinnamidoacetyl]-N-methylamino]benzyloxy]-2-methyl-4-(2-pyridylmethoxy)quinoline) was investigated. 2. Intradermal injection of FR190997 (0.03–3 nmol site(−1))...

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Detalhes bibliográficos
Main Authors: Hayashi, Izumi, Ishihara, Keiko, Kumagai, Yuji, Majima, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621159/
https://ncbi.nlm.nih.gov/pubmed/11498515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704208
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