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Metallopeptidase inhibition potentiates bradykinin-induced hyperalgesia

The neuropeptide bradykinin (BK) sensitizes nociceptor activation following its release in response to inflammatory injury. Thereafter, the bioactivity of bradykinin is controlled by the enzymatic activities of circulating peptidases. One such enzyme, the metalloendopeptidase EC3.4.24.15 (EP24.15),...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Gomez, Ruben, Por, Elaine D., Berg, Kelly A., Clarke, William P., Glucksman, Marc J., Jeske, Nathaniel A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114295/
https://ncbi.nlm.nih.gov/pubmed/21458920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.02.044
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