Angiogenesis-independent tumor growth mediated by stem-like cancer cells

In this work, highly infiltrative brain tumors with a stem-like phenotype were established by xenotransplantation of human brain tumors in immunodeficient nude rats. These tumors coopted the host vasculature and presented as an aggressive disease without signs of angiogenesis. The malignant cells ex...

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Detalhes bibliográficos
Main Authors: Sakariassen, Per Ø., Prestegarden, Lars, Wang, Jian, Skaftnesmo, Kai-Ove, Mahesparan, Rupavathana, Molthoff, Carla, Sminia, Peter, Sundlisæter, Eirik, Misra, Anjan, Tysnes, Berit Bølge, Chekenya, Martha, Peters, Hans, Lende, Gabriel, Kalland, Karl Henning, Øyan, Anne M., Petersen, Kjell, Jonassen, Inge, van der Kogel, Albert, Feuerstein, Burt G., Terzis, A. Jorge A., Bjerkvig, Rolf, Enger, Per Øyvind
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618812/
https://ncbi.nlm.nih.gov/pubmed/17056721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607668103
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