The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells

INTRODUCTION: Glioblastoma multiforme (GBM; World Health Organization astrocytoma grade IV) is the most frequent and most malignant primary brain tumor in adults. Despite multimodal therapy, all such tumors practically recur during the course of therapy, causing a median survival of only 14.6 months...

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Detaylı Bibliyografya
Asıl Yazarlar: Johannessen, Tor-Christian Aase, Prestegarden, Lars, Grudic, Amra, Hegi, Monika E., Tysnes, Berit Bølge, Bjerkvig, Rolf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
Konular:
Basic and Translational Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578482/
https://ncbi.nlm.nih.gov/pubmed/23258843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos301
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