DS-04 DOPAMINE ADDICTION IN GLIOBLASTOMA MULTIFORME DURING CHEMOTHERAPY IS MEDIATED BY A DRD2/β-ARRESTIN/AKT SIGNALING COMPLEX

Glioblastomas are highly resistant to therapy and carries a dismal prognosis. Standard of care includes surgery followed by radiotherapy (RT) with concurrent and adjuvant chemotherapy with temozolomide (TMZ). The addition of TMZ to RT increases the overall survival by approximately 3 months compared...

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Autori principali: Prestegarden, Lars, Johannessen, Tor-Christian, Grudic, Amra, Sundstrøm, Terje, Saed, Halala, Varughese, Jobin, Lund-Johansen, Morten, Bjerkvig, Rolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218027/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou244.4
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