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P01.19 A GENOME-WIDE RNAI SYNTHETIC LETHAL SCREEN FOR SENSITIZERS OF GLIOBLASTOMA MULTIFORME TO TEMOZOLOMIDE

Glioblastoma multiforme (GBM) is highly resistant to therapy and carries a dismal prognosis. Standard of care includes surgery followed by radiotherapy (RT) with concurrent and adjuvant chemotherapy with temozolomide (TMZ). The addition of TMZ to RT increases the overall survival by approximately 3...

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Detalhes bibliográficos
Main Authors: Johannessen, T. Aase, Grudic, A., Sundstrøm, T., Varughese, J.K., Lund-Johansen, M., Bjerkvig, R., Prestegarden, L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185453/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.112
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