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P01.19 A GENOME-WIDE RNAI SYNTHETIC LETHAL SCREEN FOR SENSITIZERS OF GLIOBLASTOMA MULTIFORME TO TEMOZOLOMIDE
Glioblastoma multiforme (GBM) is highly resistant to therapy and carries a dismal prognosis. Standard of care includes surgery followed by radiotherapy (RT) with concurrent and adjuvant chemotherapy with temozolomide (TMZ). The addition of TMZ to RT increases the overall survival by approximately 3...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185453/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.112 |
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