A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma

BACKGROUND: Although several studies suggest that stromal fibroblasts mediate treatment resistance in several cancer types, little is known about how tumor-associated astrocytes modulate the treatment response in brain tumors. Since traditionally used metabolic assays do not distinguish metabolic ac...

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Detalhes bibliográficos
Main Authors: Yang, Ning, Yan, Tao, Zhu, Huaiyang, Liang, Xiao, Leiss, Lina, Sakariassen, Per Øystein, Skaftnesmo, Kai Ove, Huang, Bin, Costea, Daniela Elena, Enger, Per Øyvind, Li, Xingang, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198700/
https://ncbi.nlm.nih.gov/pubmed/25280402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0278-y
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