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Integrity of Cell-Cell Contacts Is a Critical Regulator of TGF-β1-Induced Epithelial-to-Myofibroblast Transition : Role for β-Catenin

Injury of the tubular epithelium and TGF-β1-induced conversion of epithelial cells to α-smooth muscle actin (SMA)-expressing myofibroblasts are key features of kidney fibrosis. Since injury damages intercellular junctions and promotes fibrosis, we hypothesized that cell contacts are critical regulat...

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Detalhes bibliográficos
Main Authors: Masszi, András, Fan, Lingzhi, Rosivall, László, McCulloch, Christopher A., Rotstein, Ori D., Mucsi, István, Kapus, András
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618715/
https://ncbi.nlm.nih.gov/pubmed/15579439
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