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Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition
Induction of epithelial–myofibroblast transition (EMyT), a robust fibrogenic phenotype change hallmarked by α-smooth muscle actin (SMA) expression, requires transforming growth factor-β1 (TGFβ) and the absence/uncoupling of intracellular contacts. This suggests that an “injured” epithelium may be to...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814143/ https://ncbi.nlm.nih.gov/pubmed/24006486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-04-0220 |
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