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Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3

Epithelial–myofibroblast (MF) transition (EMyT) is a critical process in organ fibrosis, leading to α–smooth muscle actin (SMA) expression in the epithelium. The mechanism underlying the activation of this myogenic program is unknown. We have shown previously that both injury to intercellular contac...

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Detalhes bibliográficos
Main Authors: Masszi, András, Speight, Pam, Charbonney, Emmanuel, Lodyga, Monika, Nakano, Hiroyasu, Szászi, Katalin, Kapus, András
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819691/
https://ncbi.nlm.nih.gov/pubmed/20123992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906155
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