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Cell Contact–dependent Regulation of Epithelial–Myofibroblast Transition via the Rho-Rho Kinase-Phospho-Myosin Pathway

Epithelial-mesenchymal-myofibroblast transition (EMT), a key feature in organ fibrosis, is regulated by the state of intercellular contacts. Our recent studies have shown that an initial injury of cell–cell junctions is a prerequisite for transforming growth factor-β1 (TGF-β1)-induced transdifferent...

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Hlavní autoři: Fan, Lingzhi, Sebe, Attila, Péterfi, Zalán, Masszi, András, Thirone, Ana C.P., Rotstein, Ori D., Nakano, Hiroyasu, McCulloch, Christopher A., Szászi, Katalin, Mucsi, István, Kapus, András
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805104/
https://ncbi.nlm.nih.gov/pubmed/17215519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-07-0602
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