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Mice Deficient in Glutathione Transferase Zeta/Maleylacetoacetate Isomerase Exhibit a Range of Pathological Changes and Elevated Expression of Alpha, Mu, and Pi Class Glutathione Transferases

Glutathione transferase zeta (GSTZ1-1) is the major enzyme that catalyzes the metabolism of α-halo acids such as dichloroacetic acid, a carcinogenic contaminant of chlorinated water. GSTZ1-1 is identical with maleylacetoacetate isomerase, which catalyzes the penultimate step in the catabolic pathway...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lim, Cindy E.L., Matthaei, Klaus I., Blackburn, Anneke C., Davis, Richard P., Dahlstrom, Jane E., Koina, Mark E., Anders, M.W., Board, Philip G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618558/
https://ncbi.nlm.nih.gov/pubmed/15277241
Tagiau: Ychwanegu Tag
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