Mice Deficient in Glutathione Transferase Zeta/Maleylacetoacetate Isomerase Exhibit a Range of Pathological Changes and Elevated Expression of Alpha, Mu, and Pi Class Glutathione Transferases

Glutathione transferase zeta (GSTZ1-1) is the major enzyme that catalyzes the metabolism of α-halo acids such as dichloroacetic acid, a carcinogenic contaminant of chlorinated water. GSTZ1-1 is identical with maleylacetoacetate isomerase, which catalyzes the penultimate step in the catabolic pathway...

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Bibliografiset tiedot
Päätekijät: Lim, Cindy E.L., Matthaei, Klaus I., Blackburn, Anneke C., Davis, Richard P., Dahlstrom, Jane E., Koina, Mark E., Anders, M.W., Board, Philip G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2004
Aiheet:
Animal Models
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618558/
https://ncbi.nlm.nih.gov/pubmed/15277241
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