Using Cardiovascular Cells from Human Pluripotent Stem Cells for COVID-19 Research: Why the Heart Fails

por Yiangou, Loukia, Davis, Richard P., Mummery, Christine L.
Publicado en Stem Cell Reports (2020)

Inherited cardiac diseases, pluripotent stem cells, and genome editing combined—the past, present, and future

por van den Brink, Lettine, Grandela, Catarina, Mummery, Christine L., Davis, Richard P.
Publicado en Stem Cells (2019)

CRISPR/Cas9-Mediated Introduction of Specific Heterozygous Mutations in Human Induced Pluripotent Stem Cells

por Brandão, Karina O., Grandela, Catarina, Yiangou, Loukia, Mummery, Christine L., Davis, Richard P.
Publicado en Methods Mol Biol (2022)

Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies

por Brandão, Karina O., Tabel, Viola A., Atsma, Douwe E., Mummery, Christine L., Davis, Richard P.
Publicado en Dis Model Mech (2017)

WNT3A Promotes Hematopoietic or Mesenchymal Differentiation from hESCs Depending on the Time of Exposure

por Gertow, Karin, Hirst, Claire E., Yu, Qing C., Ng, Elizabeth S., Pereira, Lloyd A., Davis, Richard P., Stanley, Edouard G., Elefanty, Andrew G.
Publicado 2013

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

por van Meer, Berend J., Krotenberg, Ana, Sala, Luca, Davis, Richard P., Eschenhagen, Thomas, Denning, Chris, Tertoolen, Leon G. J., Mummery, Christine L.
Publicado en Nat Commun (2019)

Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties

por van den Brink, Lettine, Brandão, Karina O., Yiangou, Loukia, Mol, Mervyn P.H., Grandela, Catarina, Mummery, Christine L., Verkerk, Arie O., Davis, Richard P.
Publicado en Stem Cell Res (2020)

Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells

por Campostrini, Giulia, Meraviglia, Viviana, Giacomelli, Elisa, van Helden, Ruben W.J., Yiangou, Loukia, Davis, Richard P., Bellin, Milena, Orlova, Valeria V., Mummery, Christine L.
Publicado en Nat Protoc (2021)

Mice Deficient in Glutathione Transferase Zeta/Maleylacetoacetate Isomerase Exhibit a Range of Pathological Changes and Elevated Expression of Alpha, Mu, and Pi Class Glutathione T...

por Lim, Cindy E.L., Matthaei, Klaus I., Blackburn, Anneke C., Davis, Richard P., Dahlstrom, Jane E., Koina, Mark E., Anders, M.W., Board, Philip G.
Publicado 2004

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes

por Schwach, Verena, Verkerk, Arie O., Mol, Mervyn, Monshouwer-Kloots, Jantine J., Devalla, Harsha D., Orlova, Valeria V., Anastassiadis, Konstantinos, Mummery, Christine L., Davis, Richard P., Passier, Robert
Publicado en Stem Cell Reports (2017)

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

por Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L
Publicado 2013

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function

por Birket, Matthew J., Ribeiro, Marcelo C., Kosmidis, Georgios, Ward, Dorien, Leitoguinho, Ana Rita, van de Pol, Vera, Dambrot, Cheryl, Devalla, Harsha D., Davis, Richard P., Mastroberardino, Pier G., Atsma, Douwe E., Passier, Robert, Mummery, Christine L.
Publicado en Cell Rep (2015)

Differential effects on out-of-hospital cardiac arrest of dihydropyridines: real-world data from population-based cohorts across two European countries

por Eroglu, Talip E, Mohr, Grimur H, Blom, Marieke T, Verkerk, Arie O, Souverein, Patrick C, Torp-Pedersen, Christian, Folke, Fredrik, Wissenberg, Mads, van den Brink, Lettine, Davis, Richard P, de Boer, Anthonius, Gislason, Gunnar H, Tan, Hanno L
Publicado en Eur Heart J Cardiovasc Pharmacother (2019)

Leadership Training in Endocrinology Fellowship? A Survey of Program Directors and Recent Graduates

por True, Mark W., Folaron, Irene, Wardian, Jana L., Colburn, Jeffrey A., Sauerwein, Tom J., Beckman, Darrick J., Kluesner, Joseph K., Tate, Joshua M., Graybill, Sky D., Davis, Richard P., Paulus, Andrew O., Carlsen, David R., Lewi, Jack E.
Publicado en J Endocr Soc (2017)

Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias

por Brandão, Karina O., van den Brink, Lettine, Miller, Duncan C., Grandela, Catarina, van Meer, Berend J., Mol, Mervyn P.H., de Korte, Tessa, Tertoolen, Leon G.J., Mummery, Christine L., Sala, Luca, Verkerk, Arie O., Davis, Richard P.
Publicado en Stem Cell Reports (2020)

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells

por Gomes Fernandes, Maria, Dries, Ruben, Roost, Matthias S., Semrau, Stefan, de Melo Bernardo, Ana, Davis, Richard P., Ramakrishnan, Ramprasad, Szuhai, Karoly, Maas, Elke, Umans, Lieve, Abon Escalona, Vanesa, Salvatori, Daniela, Deforce, Dieter, Van Criekinge, Wim, Huylebroeck, Danny, Mummery, Christine, Zwijsen, An, Chuva de Sousa Lopes, Susana M.
Publicado en Stem Cell Reports (2015)

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo

por Sala, Luca, van Meer, Berend J., Tertoolen, Leon G.J., Bakkers, Jeroen, Bellin, Milena, Davis, Richard P., Denning, Chris, Dieben, Michel A.E., Eschenhagen, Thomas, Giacomelli, Elisa, Grandela, Catarina, Hansen, Arne, Holman, Eduard R., Jongbloed, Monique R.M., Kamel, Sarah M., Koopman, Charlotte D., Lachaud, Quentin, Mannhardt, Ingra, Mol, Mervyn P.H., Mosqueira, Diogo, Orlova, Valeria V., Passier, Robert, Ribeiro, Marcelo C., Saleem, Umber, Smith, Godfrey L., Burton, Francis L., Mummery, Christine L.
Publicado en Circ Res (2018)

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

por Anderson, David J., Kaplan, David I., Bell, Katrina M., Koutsis, Katerina, Haynes, John M., Mills, Richard J., Phelan, Dean G., Qian, Elizabeth L., Leitoguinho, Ana Rita, Arasaratnam, Deevina, Labonne, Tanya, Ng, Elizabeth S., Davis, Richard P., Casini, Simona, Passier, Robert, Hudson, James E., Porrello, Enzo R., Costa, Mauro W., Rafii, Arash, Curl, Clare L., Delbridge, Lea M., Harvey, Richard P., Oshlack, Alicia, Cheung, Michael M., Mummery, Christine L., Petrou, Stephen, Elefanty, Andrew G., Stanley, Edouard G., Elliott, David A.
Publicado en Nat Commun (2018)

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

por Giacomelli, Elisa, Meraviglia, Viviana, Campostrini, Giulia, Cochrane, Amy, Cao, Xu, van Helden, Ruben W.J., Krotenberg Garcia, Ana, Mircea, Maria, Kostidis, Sarantos, Davis, Richard P., van Meer, Berend J., Jost, Carolina R., Koster, Abraham J., Mei, Hailiang, Míguez, David G., Mulder, Aat A., Ledesma-Terrón, Mario, Pompilio, Giulio, Sala, Luca, Salvatori, Daniela C.F., Slieker, Roderick C., Sommariva, Elena, de Vries, Antoine A.F., Giera, Martin, Semrau, Stefan, Tertoolen, Leon G.J., Orlova, Valeria V., Bellin, Milena, Mummery, Christine L.
Publicado en Cell Stem Cell (2020)