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Inherited cardiac diseases, pluripotent stem cells, and genome editing combined—the past, present, and future

Research on mechanisms underlying monogenic cardiac diseases such as primary arrhythmias and cardiomyopathies has until recently been hampered by inherent limitations of heterologous cell systems, where mutant genes are expressed in noncardiac cells, and physiological differences between humans and...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: van den Brink, Lettine, Grandela, Catarina, Mummery, Christine L., Davis, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027796/
https://ncbi.nlm.nih.gov/pubmed/31664757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3110
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