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Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have emerged as a powerful platform for in vitro modelling of cardiac diseases, safety pharmacology and drug screening. All these applications require large quantities of well-characterised and standardised batches of hiPSC-CMs....

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: van den Brink, Lettine, Brandão, Karina O., Yiangou, Loukia, Mol, Mervyn P.H., Grandela, Catarina, Mummery, Christine L., Verkerk, Arie O., Davis, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611364/
https://ncbi.nlm.nih.gov/pubmed/31945612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2019.101698
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