Nalaganje...

Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid.

Dichloroacetic acid (DCA), a common drinking-water contaminant, is hepatocarcinogenic in rats and mice, and is a therapeutic agent used clinically in the management of lactic acidosis. DCA is biotransformed to glyoxylic acid by glutathione-dependent cytosolic enzymes in vitro and is metabolized to g...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Tong, Z, Board, P G, Anders, M W
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219363/
https://ncbi.nlm.nih.gov/pubmed/9531472
Oznake: Označite
Brez oznak, prvi označite!