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Investigation into the role of P2X(3)/P2X(2/3) receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study
1. Two P2X(3)/P2X(2/3) receptor antagonists with different potencies were profiled electrophysiologically in a rat model of nerve injury. 2. A-317491 has poor CNS penetrance (blood : brain, 1 : <0.05), and was therefore administered intravenously in chronic constriction injury (CCI)- and sham-ope...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1617075/ https://ncbi.nlm.nih.gov/pubmed/16770326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706790 |
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