Intrathecal leptin inhibits expression of the P2X(2/3) receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury

BACKGROUND: Leptin, an adipocytokine produced mainly by white adipose tissue, has a broad role in the regulation of neuronal functions. Accumulating evidence has revealed that leptin plays an important role in influencing neuropathic pain, shown recently by the finding that chronic administration of...

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Bibliografiske detaljer
Main Authors: Li, Xin, Kang, Lumei, Li, Guilin, Zeng, Huihong, Zhang, Lei, Ling, Xiang, Dong, Hui, Liang, Shangdong, Chen, Hongping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029482/
https://ncbi.nlm.nih.gov/pubmed/24325936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-65
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