Intrathecal leptin inhibits expression of the P2X(2/3) receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury

BACKGROUND: Leptin, an adipocytokine produced mainly by white adipose tissue, has a broad role in the regulation of neuronal functions. Accumulating evidence has revealed that leptin plays an important role in influencing neuropathic pain, shown recently by the finding that chronic administration of...

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Autors principals: Li, Xin, Kang, Lumei, Li, Guilin, Zeng, Huihong, Zhang, Lei, Ling, Xiang, Dong, Hui, Liang, Shangdong, Chen, Hongping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029482/
https://ncbi.nlm.nih.gov/pubmed/24325936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-65
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