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Stretching the Immunoglobulin 27 Domain of the Titin Protein: The Dynamic Energy Landscape

Molecular simulations are carried out on the Immunoglobulin 27 domain of the titin protein. The energy landscape is mapped out using an implicit solvent model, and molecular dynamics simulations are run with the solvent explicitly modeled. Stretching a protein is shown to produce a dynamic energy la...

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Bibliografiske detaljer
Main Authors: Duff, Nathan, Duong, N.-H., Lacks, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614469/
https://ncbi.nlm.nih.gov/pubmed/16905608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.074278
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