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Simulated refolding of stretched titin immunoglobulin domains.

Steered molecular dynamics (SMD) is used to investigate forced unfolding and spontaneous refolding of immunoglobulin I27, a domain of the muscle protein titin. Previous SMD simulations revealed the events leading to stretch-induced unfolding of I27, the rupture of hydrogen bonds bridging beta-strand...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gao, M, Lu, H, Schulten, K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301698/
https://ncbi.nlm.nih.gov/pubmed/11566797
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