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Stretching the Immunoglobulin 27 Domain of the Titin Protein: The Dynamic Energy Landscape

Molecular simulations are carried out on the Immunoglobulin 27 domain of the titin protein. The energy landscape is mapped out using an implicit solvent model, and molecular dynamics simulations are run with the solvent explicitly modeled. Stretching a protein is shown to produce a dynamic energy la...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duff, Nathan, Duong, N.-H., Lacks, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614469/
https://ncbi.nlm.nih.gov/pubmed/16905608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.074278
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