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Energy Landscape Distortions and the Mechanical Unfolding of Proteins
Molecular simulations and an energy landscape analysis are used to examine the stretching of a model protein. A mapping of the energy landscape shows that stretching the protein causes energy minima and energy barriers to flatten out and disappear, and new energy minima to be created. The implicatio...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biophysical Society
2005
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1305495/ https://ncbi.nlm.nih.gov/pubmed/15731385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051953 |
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