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Energy Landscape Distortions and the Mechanical Unfolding of Proteins

Molecular simulations and an energy landscape analysis are used to examine the stretching of a model protein. A mapping of the energy landscape shows that stretching the protein causes energy minima and energy barriers to flatten out and disappear, and new energy minima to be created. The implicatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Lacks, Daniel J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305495/
https://ncbi.nlm.nih.gov/pubmed/15731385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051953
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