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Dynamics of Equilibrium Folding and Unfolding Transitions of Titin Immunoglobulin Domain under Constant Forces

The mechanical stability of force-bearing proteins is crucial for their functions. However, slow transition rates of complex protein domains have made it challenging to investigate their equilibrium force-dependent structural transitions. Using ultra stable magnetic tweezers, we report the first equ...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Chen, Hu, Yuan, Guohua, Winardhi, Ricksen S., Yao, Mingxi, Popa, Ionel, Fernandez, Julio M., Yan, Jie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446711/
https://ncbi.nlm.nih.gov/pubmed/25726700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5119368
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