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Simulated refolding of stretched titin immunoglobulin domains.

Steered molecular dynamics (SMD) is used to investigate forced unfolding and spontaneous refolding of immunoglobulin I27, a domain of the muscle protein titin. Previous SMD simulations revealed the events leading to stretch-induced unfolding of I27, the rupture of hydrogen bonds bridging beta-strand...

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Bibliografische gegevens
Hoofdauteurs: Gao, M, Lu, H, Schulten, K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301698/
https://ncbi.nlm.nih.gov/pubmed/11566797
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