Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL

In a newly isolated temperature-sensitive lethal Escherichia coli mutant affecting the chaperonin GroEL, we observed wholesale aggregation of newly translated proteins. After temperature shift, transcription, translation, and growth slowed over two to three generations, accompanied by filamentation...

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Hauptverfasser: Chapman, Eli, Farr, George W., Usaite, Renata, Furtak, Krystyna, Fenton, Wayne A., Chaudhuri, Tapan K., Hondorp, Elise R., Matthews, Rowena G., Wolf, Sharon G., Yates, John R., Pypaert, Marc, Horwich, Arthur L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613232/
https://ncbi.nlm.nih.gov/pubmed/17043235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607534103
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