Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL

In a newly isolated temperature-sensitive lethal Escherichia coli mutant affecting the chaperonin GroEL, we observed wholesale aggregation of newly translated proteins. After temperature shift, transcription, translation, and growth slowed over two to three generations, accompanied by filamentation...

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Detalhes bibliográficos
Main Authors: Chapman, Eli, Farr, George W., Usaite, Renata, Furtak, Krystyna, Fenton, Wayne A., Chaudhuri, Tapan K., Hondorp, Elise R., Matthews, Rowena G., Wolf, Sharon G., Yates, John R., Pypaert, Marc, Horwich, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613232/
https://ncbi.nlm.nih.gov/pubmed/17043235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607534103
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