Improved Survival of Ischemic Cutaneous and Musculocutaneous Flaps after Vascular Endothelial Growth Factor Gene Transfer Using Adeno-Associated Virus Vectors

A major challenge in reconstructive surgery is flap ischemia, which might benefit from induction of therapeutic angiogenesis. Here we demonstrate the effect of an adeno-associated virus (AAV) vector delivering vascular endothelial growth factor (VEGF)165 in two widely recognized in vivo flap models....

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Detalhes bibliográficos
Main Authors: Zacchigna, Serena, Papa, Giovanni, Antonini, Andrea, Novati, Federico, Moimas, Silvia, Carrer, Alessandro, Arsic, Nikola, Zentilin, Lorena, Visintini, Valentina, Pascone, Michele, Giacca, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
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Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603677/
https://ncbi.nlm.nih.gov/pubmed/16192634
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