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Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction
Viral vectors based on the adeno-associated virus (AAV) hold great promise for in vivo gene transfer; several unknowns, however, still limit the vectors’ broader and more efficient application. Here, we report the results of a high-throughput, whole-genome siRNA screening aimed at identifying cellul...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568673/ https://ncbi.nlm.nih.gov/pubmed/26305933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503607112 |
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