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Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction

Viral vectors based on the adeno-associated virus (AAV) hold great promise for in vivo gene transfer; several unknowns, however, still limit the vectors’ broader and more efficient application. Here, we report the results of a high-throughput, whole-genome siRNA screening aimed at identifying cellul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Mano, Miguel, Ippodrino, Rudy, Zentilin, Lorena, Zacchigna, Serena, Giacca, Mauro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568673/
https://ncbi.nlm.nih.gov/pubmed/26305933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503607112
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