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Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry

The enveloped alphaviruses include important and emerging human pathogens such as Chikungunya virus and Eastern equine encephalitis virus. Alphaviruses enter cells by clathrin-mediated endocytosis, and exit by budding from the plasma membrane. While there has been considerable progress in defining t...

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Bibliographic Details
Main Authors: Ooi, Yaw Shin, Stiles, Katie M., Liu, Catherine Y., Taylor, Gwen M., Kielian, Margaret
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868536/
https://ncbi.nlm.nih.gov/pubmed/24367265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003835
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