Nerve Growth Factor Gene Therapy Using Adeno-Associated Viral Vectors Prevents Cardiomyopathy in Type 1 Diabetic Mice

Diabetes is a cause of cardiac dysfunction, reduced myocardial perfusion, and ultimately heart failure. Nerve growth factor (NGF) exerts protective effects on the cardiovascular system. This study investigated whether NGF gene transfer can prevent diabetic cardiomyopathy in mice. We worked with mice...

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Hlavní autoři: Meloni, Marco, Descamps, Betty, Caporali, Andrea, Zentilin, Lorena, Floris, Ilaria, Giacca, Mauro, Emanueli, Costanza
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2012
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237667/
https://ncbi.nlm.nih.gov/pubmed/22187379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0763
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