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Nerve Growth Factor Gene Therapy Using Adeno-Associated Viral Vectors Prevents Cardiomyopathy in Type 1 Diabetic Mice

Diabetes is a cause of cardiac dysfunction, reduced myocardial perfusion, and ultimately heart failure. Nerve growth factor (NGF) exerts protective effects on the cardiovascular system. This study investigated whether NGF gene transfer can prevent diabetic cardiomyopathy in mice. We worked with mice...

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Detalhes bibliográficos
Main Authors: Meloni, Marco, Descamps, Betty, Caporali, Andrea, Zentilin, Lorena, Floris, Ilaria, Giacca, Mauro, Emanueli, Costanza
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237667/
https://ncbi.nlm.nih.gov/pubmed/22187379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0763
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