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Nerve Growth Factor Gene Therapy Using Adeno-Associated Viral Vectors Prevents Cardiomyopathy in Type 1 Diabetic Mice

Diabetes is a cause of cardiac dysfunction, reduced myocardial perfusion, and ultimately heart failure. Nerve growth factor (NGF) exerts protective effects on the cardiovascular system. This study investigated whether NGF gene transfer can prevent diabetic cardiomyopathy in mice. We worked with mice...

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Bibliografiske detaljer
Main Authors: Meloni, Marco, Descamps, Betty, Caporali, Andrea, Zentilin, Lorena, Floris, Ilaria, Giacca, Mauro, Emanueli, Costanza
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237667/
https://ncbi.nlm.nih.gov/pubmed/22187379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0763
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