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Involvement of Cellular Double-Stranded DNA Break Binding Proteins in Processing of the Recombinant Adeno-Associated Virus Genome

Unlike postmitotic tissues in vivo, transduction of cultured cells is poor with recombinant adeno-associated virus (rAAV). The ability of rAAV to transduce cells is greatly enhanced by a variety of agents that induce DNA damage and is elevated in cells defective in the ataxia telangiectasia gene pro...

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Detalhes bibliográficos
Main Authors: Zentilin, Lorena, Marcello, Alessandro, Giacca, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116124/
https://ncbi.nlm.nih.gov/pubmed/11711618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12279-12287.2001
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