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Involvement of Cellular Double-Stranded DNA Break Binding Proteins in Processing of the Recombinant Adeno-Associated Virus Genome
Unlike postmitotic tissues in vivo, transduction of cultured cells is poor with recombinant adeno-associated virus (rAAV). The ability of rAAV to transduce cells is greatly enhanced by a variety of agents that induce DNA damage and is elevated in cells defective in the ataxia telangiectasia gene pro...
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Format: | Artigo |
Jezik: | Inglês |
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American Society for Microbiology
2001
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC116124/ https://ncbi.nlm.nih.gov/pubmed/11711618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12279-12287.2001 |
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