Establishment of a Diabetic Mouse Model with Progressive Diabetic Nephropathy

Although diabetic animal models exist, no single animal model develops renal changes identical to those seen in humans. Here we show that transgenic mice that overexpress inducible cAMP early repressor (ICER Iγ) in pancreatic β cells are a good model to study the pathogenesis of diabetic nephropathy...

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Detalles Bibliográficos
Main Authors: Inada, Akari, Nagai, Kojiro, Arai, Hidenori, Miyazaki, Jun-ichi, Nomura, Keiko, Kanamori, Hiroshi, Toyokuni, Shinya, Yamada, Yuichiro, Bonner-Weir, Susan, Weir, Gordon C., Fukatsu, Atsushi, Seino, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603579/
https://ncbi.nlm.nih.gov/pubmed/16049320
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