Overexpression of Inducible Cyclic AMP Early Repressor Inhibits Transactivation of Genes and Cell Proliferation in Pancreatic β Cells

Transcriptional control mediated by the cyclic AMP-responsive element (CRE) represents an important mechanism of gene regulation. To test our hypothesis that increased inducible cyclic AMP early repressor (ICER) Iγ inhibits function of CRE-binding proteins and thus disrupts CRE-mediated transcriptio...

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Detalhes bibliográficos
Main Authors: Inada, Akari, Hamamoto, Yoshiyuki, Tsuura, Yoshiyuki, Miyazaki, Jun-ichi, Toyokuni, Shinya, Ihara, Yu, Nagai, Koichiro, Yamada, Yuichiro, Bonner-Weir, Susan, Seino, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371116/
https://ncbi.nlm.nih.gov/pubmed/15024072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2831-2841.2004
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