Adjusting the 17β–Estradiol-to-Androgen Ratio Ameliorates Diabetic Nephropathy

Diabetes is manifested predominantly in males in experimental models, and compelling evidence suggests that 17β-estradiol (E2) supplementation improves hyperglycemia in humans. We previously generated a severely diabetic transgenic (Tg) mouse model by β-cell–specific overexpression of inducible cAMP...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Inada, Akari, Inada, Oogi, Fujii, Nobuharu L., Nagafuchi, Seiho, Katsuta, Hitoshi, Yasunami, Yohichi, Matsubara, Takeshi, Arai, Hidenori, Fukatsu, Atsushi, Nabeshima, Yo-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042662/
https://ncbi.nlm.nih.gov/pubmed/26940099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015070741
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