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Lung Alveolar Septation Defects in Ltbp-3-Null Mice
Latent transforming growth factor (TGF)-β binding proteins (LTBPs) modulate the secretion and activation of latent TGF-β. To explore LTBP function in vivo, we created an Ltbp-3(−/−) mouse that has developmental emphysema with decreased septation in terminal alveoli. Differences in distal airspace en...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Investigative Pathology
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1603559/ https://ncbi.nlm.nih.gov/pubmed/16049328 |
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