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Up-Regulation of Inhibitors of Protein Phosphatase-2A in Alzheimer’s Disease
The activity of protein phosphatase-2A (PP2A) is compromised and is believed to be a cause of the abnormal hyperphosphorylation of tau in Alzheimer’s disease (AD) brain. We investigated in AD the role of the two known endogenous PP2A inhibitors, called I(1)(PP2A) and I(2)(PP2A), which regulate the i...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Investigative Pathology
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1602412/ https://ncbi.nlm.nih.gov/pubmed/15920161 |
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