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Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration

Microtubule associated protein (MAP) tau is abnormally hyperphosphorylated in Alzheimer’s disease (AD) and related tauopathies; in this form it is the major protein subunit of paired helical filaments (PHF)/neurofibrillary tangles. However, the nature of protein kinases and phosphatases and tau site...

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Detalhes bibliográficos
Main Authors: Wang, Jian-Zhi, Grundke-Iqbal, Inge, Iqbal, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191918/
https://ncbi.nlm.nih.gov/pubmed/17241267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.05226.x
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