Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases

Tau is a neuronal microtubule-associated protein. Its hyperphosphorylation plays a critical role in Alzheimer disease (AD). Expression and phosphorylation of tau are regulated developmentally, but its dynamic regulation and the responsible kinases or phosphatases remain elusive. Here, we studied the...

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Bibliographic Details
Main Authors: Yu, Yang, Run, Xiaoqin, Liang, Zhihou, Li, Yi, Liu, Fei, Liu, Ying, Iqbal, Khalid, Grundke-Iqbal, Inge, Gong, Cheng-Xin
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676439/
https://ncbi.nlm.nih.gov/pubmed/19183272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05882.x
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